Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model.
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| Title: | Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model. |
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| Authors: | Zhang H; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Anesthesia, Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou 310006, China., Zhao H; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China., Zeng C; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Health Management Center, Xiangya Hospital, Central South University, Changsha 410008, China., Van Dort C; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA; Picower Institute for Learning and Memory, MIT, Cambridge, MA 02139, USA., Faingold CL; Department of Pharmacology and Neurology, Division of Neurosurgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA., Taylor NE; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA., Solt K; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA., Feng HJ; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA. Electronic address: feng.huajun@mgh.harvard.edu. |
| Source: | Neurobiology of disease [Neurobiol Dis] 2018 Feb; Vol. 110, pp. 47-58. Date of Electronic Publication: 2017 Nov 13. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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