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Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.

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Bibliographic Details
Title: Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.
Authors: Butler CR; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Beck EM; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Harris A; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Huang Z; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., McAllister LA; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Am Ende CW; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Fennell K; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Foley TL; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Fonseca K; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Hawrylik SJ; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Johnson DS; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Knafels JD; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Mente S; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Noell GS; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Pandit J; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Phillips TB; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Piro JR; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Rogers BN; Pfizer Worldwide Research and Development , 445 Eastern Point Road, Groton, Connecticut 06340, United States., Samad TA; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Wang J; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China., Wan S; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China., Brodney MA; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2017 Dec 14; Vol. 60 (23), pp. 9860-9873. Date of Electronic Publication: 2017 Dec 05.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4804
DOI:10.1021/acs.jmedchem.7b01531