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Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.

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Title: Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.
Authors: Tomlin FM; Department of Chemistry, Stanford University, Stanford, California 94305, United States., Gerling-Driessen UIM; Department of Chemistry, Stanford University, Stanford, California 94305, United States., Liu YC; Department of Chemistry, Stanford University, Stanford, California 94305, United States., Flynn RA; Department of Chemistry, Stanford University, Stanford, California 94305, United States., Vangala JR; Department of Pathology, Virginia Commonwealth University, Richmond, Virginia 23298, United States., Lentz CS; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States., Clauder-Muenster S; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany., Jakob P; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany., Mueller WF; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany., Ordoñez-Rueda D; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany., Paulsen M; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany., Matsui N; Glycomine, Inc., 953 Indiana Street, San Francisco, California 94107, United States., Foley D; Glycomine, Inc., 953 Indiana Street, San Francisco, California 94107, United States., Rafalko A; Glycomine, Inc., 953 Indiana Street, San Francisco, California 94107, United States., Suzuki T; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN Global Research Cluster, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan., Bogyo M; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States.; Department of Microbiology and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States., Steinmetz LM; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.; Department of Genetics, School of Medicine, Stanford University, Stanford, California 94305, United States., Radhakrishnan SK; Department of Pathology, Virginia Commonwealth University, Richmond, Virginia 23298, United States., Bertozzi CR; Department of Chemistry, Stanford University, Stanford, California 94305, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States.
Source: ACS central science [ACS Cent Sci] 2017 Nov 22; Vol. 3 (11), pp. 1143-1155. Date of Electronic Publication: 2017 Oct 25.
Publication Type: Journal Article
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101660035 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2374-7943 (Print) Linking ISSN: 23747943 NLM ISO Abbreviation: ACS Cent Sci Subsets: PubMed not MEDLINE
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  Data: Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.
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  Data: <searchLink fieldCode="AU" term="%22Tomlin+FM%22">Tomlin FM</searchLink>; Department of Chemistry, Stanford University, Stanford, California 94305, United States.<br /><searchLink fieldCode="AU" term="%22Gerling-Driessen+UIM%22">Gerling-Driessen UIM</searchLink>; Department of Chemistry, Stanford University, Stanford, California 94305, United States.<br /><searchLink fieldCode="AU" term="%22Liu+YC%22">Liu YC</searchLink>; Department of Chemistry, Stanford University, Stanford, California 94305, United States.<br /><searchLink fieldCode="AU" term="%22Flynn+RA%22">Flynn RA</searchLink>; Department of Chemistry, Stanford University, Stanford, California 94305, United States.<br /><searchLink fieldCode="AU" term="%22Vangala+JR%22">Vangala JR</searchLink>; Department of Pathology, Virginia Commonwealth University, Richmond, Virginia 23298, United States.<br /><searchLink fieldCode="AU" term="%22Lentz+CS%22">Lentz CS</searchLink>; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States.<br /><searchLink fieldCode="AU" term="%22Clauder-Muenster+S%22">Clauder-Muenster S</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jakob+P%22">Jakob P</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mueller+WF%22">Mueller WF</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ordoñez-Rueda+D%22">Ordoñez-Rueda D</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Paulsen+M%22">Paulsen M</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Matsui+N%22">Matsui N</searchLink>; Glycomine, Inc., 953 Indiana Street, San Francisco, California 94107, United States.<br /><searchLink fieldCode="AU" term="%22Foley+D%22">Foley D</searchLink>; Glycomine, Inc., 953 Indiana Street, San Francisco, California 94107, United States.<br /><searchLink fieldCode="AU" term="%22Rafalko+A%22">Rafalko A</searchLink>; Glycomine, Inc., 953 Indiana Street, San Francisco, California 94107, United States.<br /><searchLink fieldCode="AU" term="%22Suzuki+T%22">Suzuki T</searchLink>; Glycometabolome Team, Systems Glycobiology Research Group, RIKEN Global Research Cluster, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.<br /><searchLink fieldCode="AU" term="%22Bogyo+M%22">Bogyo M</searchLink>; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States.; Department of Microbiology and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States.<br /><searchLink fieldCode="AU" term="%22Steinmetz+LM%22">Steinmetz LM</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.; Department of Genetics, School of Medicine, Stanford University, Stanford, California 94305, United States.<br /><searchLink fieldCode="AU" term="%22Radhakrishnan+SK%22">Radhakrishnan SK</searchLink>; Department of Pathology, Virginia Commonwealth University, Richmond, Virginia 23298, United States.<br /><searchLink fieldCode="AU" term="%22Bertozzi+CR%22">Bertozzi CR</searchLink>; Department of Chemistry, Stanford University, Stanford, California 94305, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States.
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  Data: <searchLink fieldCode="JN" term="%22101660035%22">ACS central science</searchLink> [ACS Cent Sci] 2017 Nov 22; Vol. 3 (11), pp. 1143-1155. <i>Date of Electronic Publication: </i>2017 Oct 25.
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