Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β.
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| Title: | Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β. |
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| Authors: | Lan Y; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA. yan.lan@emdserono.com kinming.lo@emdserono.com., Zhang D; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Xu C; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Hance KW; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Marelli B; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Qi J; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Yu H; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Qin G; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Sircar A; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Hernández VM; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Jenkins MH; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Fontana RE; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Deshpande A; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Locke G; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Sabzevari H; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Radvanyi L; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA., Lo KM; EMD Serono Research and Development Institute Inc., Billerica, MA 01821, USA. yan.lan@emdserono.com kinming.lo@emdserono.com. |
| Source: | Science translational medicine [Sci Transl Med] 2018 Jan 17; Vol. 10 (424). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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