Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.
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| Title: | Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms. |
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| Authors: | Pridgeon CS; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK., Schlott C; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK., Wong MW; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK., Heringa MB; National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Heckel T; Dr. Johannes Heidenhain GmbH, Dr.-Johannes-Heidenhain-Straße 5, 83301, Traunreut, Germany., Leedale J; Department of Mathematical Sciences, University of Liverpool, Liverpool, L69 7ZL, UK., Launay L; Technologie Servier, Orléans, France., Gryshkova V; Investigative Toxicology, Department of Non-Clinical Development, UCB Biopharma SPRL, 1420, Braine L'Alleud, Belgium., Przyborski S; Department of Biosciences, Durham University, Durham, DH1 3LE, UK., Bearon RN; Department of Mathematical Sciences, University of Liverpool, Liverpool, L69 7ZL, UK., Wilkinson EL; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK., Ansari T; Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospital, Middlesex, HA1 3UJ, UK., Greenman J; School of Life Sciences, University of Hull, Hull, HU6 7RX, UK., Hendriks DFG; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Gibbs S; Department of Dermatology, VU University Medical Center, Amsterdam, The Netherlands.; Department of Oral Cell Biology, Academic Center for Dentistry Amsterdam, University of Amsterdam and VU University, Amsterdam, The Netherlands., Sidaway J; Phenotox Ltd, Cheshire, SK10 5QT, UK., Sison-Young RL; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK., Walker P; Cyprotex Discovery Ltd, Cheshire, SK10 4TG, UK., Cross MJ; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK., Park BK; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK., Goldring CEP; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, L69 3GE, UK. chrissy@liv.ac.uk. |
| Source: | Archives of toxicology [Arch Toxicol] 2018 Feb; Vol. 92 (2), pp. 557-569. Date of Electronic Publication: 2018 Jan 23. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0738 |
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| DOI: | 10.1007/s00204-018-2152-9 |
