Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2α dephosphorylation by the GADD34/PP1c complex.
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| Title: | Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2α dephosphorylation by the GADD34/PP1c complex. |
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| Authors: | Perego J; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Mendes A; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France., Bourbon C; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Camosseto V; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France., Combes A; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Liu H; Sanofi, Cambridge, MA 02139, USA., Manh TV; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Dalet A; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Chasson L; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Spinelli L; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France., Bardin N; Laboratoire d'Immunologie, Hôpital de la Conception, 13005 Marseille, France.; Aix Marseille Université, INSERM, VRCM, 13005 Marseille, France., Chiche L; Hôpital Européen, 13003 Marseille, France., Santos MAS; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal., Gatti E; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France. gatti@ciml.univ-mrs.fr pierre@ciml.univ-mrs.fr.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal., Pierre P; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy (CIML), 13008 Marseille, France. gatti@ciml.univ-mrs.fr pierre@ciml.univ-mrs.fr.; International Associated Laboratory (LIA) CNRS 'Mistra,' 13008 Marseille, France.; Institute for Research in Biomedicine (iBiMED) and Aveiro Health Sciences Program University of Aveiro, 3810-193 Aveiro, Portugal. |
| Source: | Science signaling [Sci Signal] 2018 Jan 23; Vol. 11 (514). Date of Electronic Publication: 2018 Jan 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.aam8104 |
