Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons.

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Title: Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons.
Authors: Hervera A; Molecular Neuroregeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK.; Cellular and Molecular Neurobiotechnology, Institute for Bioengineering of Catalonia, Barcelona, Spain., De Virgiliis F; Molecular Neuroregeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK.; Laboratory for NeuroRegeneration and Repair, Center for Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate School for Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Palmisano I; Molecular Neuroregeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK., Zhou L; Laboratory for NeuroRegeneration and Repair, Center for Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Tantardini E; Molecular Neuroregeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK., Kong G; Laboratory for NeuroRegeneration and Repair, Center for Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Hutson T; Molecular Neuroregeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK., Danzi MC; The Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Perry RB; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Santos CXC; Cardiovascular Division, British Heart Foundation Centre of Research Excellence, King's College London, London, UK., Kapustin AN; Cardiovascular Division, British Heart Foundation Centre of Research Excellence, King's College London, London, UK., Fleck RA; Centre for Ultrastructural Imaging, King's College London, London, UK., Del Río JA; Cellular and Molecular Neurobiotechnology, Institute for Bioengineering of Catalonia, Barcelona, Spain.; Department of Cell Biology, Physiology and Immunology, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain., Carroll T; Bioinformatics Resource Centre, The Rockefeller University, New York, NY, USA., Lemmon V; The Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Bixby JL; The Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Shah AM; Cardiovascular Division, British Heart Foundation Centre of Research Excellence, King's College London, London, UK., Fainzilber M; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Di Giovanni S; Molecular Neuroregeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK. s.di-giovanni@imperial.ac.uk.; Laboratory for NeuroRegeneration and Repair, Center for Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. s.di-giovanni@imperial.ac.uk.
Source: Nature cell biology [Nat Cell Biol] 2018 Mar; Vol. 20 (3), pp. 307-319. Date of Electronic Publication: 2018 Feb 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4679
DOI:10.1038/s41556-018-0039-x