Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement.
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| Title: | Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement. |
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| Authors: | Ugurlar D; Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands., Howes SC; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands., de Kreuk BJ; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands., Koning RI; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands.; NeCEN, Gorlaeus Laboratories, Leiden University, 2333 CC Leiden, Netherlands., de Jong RN; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands., Beurskens FJ; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands., Schuurman J; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands., Koster AJ; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands.; NeCEN, Gorlaeus Laboratories, Leiden University, 2333 CC Leiden, Netherlands., Sharp TH; Section of Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, Netherlands. t.sharp@lumc.nl p.w.h.i.parren@lumc.nl p.gros@uu.nl., Parren PWHI; Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands. t.sharp@lumc.nl p.w.h.i.parren@lumc.nl p.gros@uu.nl.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, Netherlands., Gros P; Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands. t.sharp@lumc.nl p.w.h.i.parren@lumc.nl p.gros@uu.nl. |
| Source: | Science (New York, N.Y.) [Science] 2018 Feb 16; Vol. 359 (6377), pp. 794-797. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.aao4988 |
