Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial.

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Title: Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial.
Authors: Paul M; Institute of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel; Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel. Electronic address: paulm@technion.ac.il., Daikos GL; First Department of Medicine, Laikon General Hospital, Athens, Greece; National and Kapodistrian University of Athens, Athens, Greece., Durante-Mangoni E; Internal Medicine, University of Campania 'L Vanvitelli', and AORN dei Colli-Monaldi Hospital, Napoli, Italy., Yahav D; Unit of Infectious Diseases, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel., Carmeli Y; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel; Division of Epidemiology and Preventive Medicine, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel., Benattar YD; Institute of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel; Cheryl Spencer Department of Nursing, University of Haifa, Haifa, Israel., Skiada A; First Department of Medicine, Laikon General Hospital, Athens, Greece; National and Kapodistrian University of Athens, Athens, Greece., Andini R; Internal Medicine, University of Campania 'L Vanvitelli', and AORN dei Colli-Monaldi Hospital, Napoli, Italy., Eliakim-Raz N; Unit of Infectious Diseases, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel., Nutman A; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel; Division of Epidemiology and Preventive Medicine, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel., Zusman O; Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel., Antoniadou A; National and Kapodistrian University of Athens, Athens, Greece; Fourth Department of Medicine, Attikon University General Hospital, Athens, Greece., Pafundi PC; Internal Medicine, University of Campania 'L Vanvitelli', and AORN dei Colli-Monaldi Hospital, Napoli, Italy., Adler A; Microbiology Laboratory, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel., Dickstein Y; Institute of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Pavleas I; Intensive Care Unit, Laikon General Hospital, Athens, Greece., Zampino R; Internal Medicine, University of Campania 'L Vanvitelli', and AORN dei Colli-Monaldi Hospital, Napoli, Italy., Daitch V; Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel., Bitterman R; Institute of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Zayyad H; Institute of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Koppel F; Institute of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Levi I; Division of Epidemiology and Preventive Medicine, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel., Babich T; Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel., Friberg LE; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Mouton JW; Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, the Netherlands., Theuretzbacher U; Center for Anti-Infective Agents, Vienna, Austria., Leibovici L; Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel.
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2018 Apr; Vol. 18 (4), pp. 391-400. Date of Electronic Publication: 2018 Feb 16.
Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Equivalence Trial
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-4457
DOI:10.1016/S1473-3099(18)30099-9