Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe.

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Title: Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe.
Authors: Kamariza M; Department of Biology, Stanford University, Stanford, CA 94305, USA., Shieh P; Department of Chemistry, Stanford University, Stanford, CA 94305, USA., Ealand CS; Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, Faculty of Health Sciences, University of Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa., Peters JS; Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, Faculty of Health Sciences, University of Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa., Chu B; Department of Chemistry, Stanford University, Stanford, CA 94305, USA., Rodriguez-Rivera FP; Department of Chemistry, Stanford University, Stanford, CA 94305, USA., Babu Sait MR; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Duesseldorf, Universitätsstrasse 1, 40225 Duesseldorf, Germany., Treuren WV; Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA., Martinson N; Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, Faculty of Health Sciences, University of Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa.; Perinatal HIV Research Unit (PHRU), SA MRC Soweto Matlosana Collaborating Centre for HIV/AIDS and TB, University of the Witwatersrand, Johannesburg, South Africa., Kalscheuer R; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Duesseldorf, Universitätsstrasse 1, 40225 Duesseldorf, Germany., Kana BD; Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, Faculty of Health Sciences, University of Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa.; Medical Research Council-Centre for the AIDS Programme of Research in South Africa (CAPRISA) HIV-TB Pathogenesis and Treatment Research Unit, Durban, South Africa., Bertozzi CR; Department of Chemistry, Stanford University, Stanford, CA 94305, USA. bertozzi@stanford.edu.; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Source: Science translational medicine [Sci Transl Med] 2018 Feb 28; Vol. 10 (430).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.aam6310