Distinct functions for the membrane-proximal ectodomain region (MPER) of HIV-1 gp41 in cell-free and cell-cell viral transmission and cell-cell fusion.

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Title: Distinct functions for the membrane-proximal ectodomain region (MPER) of HIV-1 gp41 in cell-free and cell-cell viral transmission and cell-cell fusion.
Authors: Narasimhulu VGS; From the Virus Entry and Vaccines Laboratory, Burnet Institute, Melbourne, Victoria 3004.; the Department of Microbiology and Immunology at the Peter Doherty Institute, University of Melbourne, Parkville, Victoria 3010, and., Bellamy-McIntyre AK; From the Virus Entry and Vaccines Laboratory, Burnet Institute, Melbourne, Victoria 3004.; the Departments of Microbiology and., Laumaea AE; From the Virus Entry and Vaccines Laboratory, Burnet Institute, Melbourne, Victoria 3004.; the Department of Microbiology and Immunology at the Peter Doherty Institute, University of Melbourne, Parkville, Victoria 3010, and., Lay CS; Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia., Harrison DN; From the Virus Entry and Vaccines Laboratory, Burnet Institute, Melbourne, Victoria 3004., King HAD; From the Virus Entry and Vaccines Laboratory, Burnet Institute, Melbourne, Victoria 3004.; the Department of Microbiology and Immunology at the Peter Doherty Institute, University of Melbourne, Parkville, Victoria 3010, and., Drummer HE; From the Virus Entry and Vaccines Laboratory, Burnet Institute, Melbourne, Victoria 3004.; the Department of Microbiology and Immunology at the Peter Doherty Institute, University of Melbourne, Parkville, Victoria 3010, and.; the Departments of Microbiology and., Poumbourios P; From the Virus Entry and Vaccines Laboratory, Burnet Institute, Melbourne, Victoria 3004, andy.poumbourios@burnet.edu.au.; the Departments of Microbiology and.; Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.
Source: The Journal of biological chemistry [J Biol Chem] 2018 Apr 20; Vol. 293 (16), pp. 6099-6120. Date of Electronic Publication: 2018 Mar 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1074/jbc.RA117.000537