The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs.

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Bibliographic Details
Title: The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs.
Authors: Chiang AY; Eli Lilly and Company, Indianapolis, IN, United States., Guth BD; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany; The Preclinical Drug Development Platform, North-West University, Potchefstroom, South Africa., Pugsley MK; Purdue Pharma, LP, Stamford, CT, United States., Foley CM; AbbVie, Abbott Park, IL, United States., Doyle JM; Data Sciences International, St. Paul, MN, United States., Engwall MJ; Amgen, Thousand Oaks, CA, United States., Koerner JE; FDA, Washington DC, United States., Parish ST; HESI, Washington DC, United States. Electronic address: sparish@hesiglobal.org., Dustan Sarazan R; Independent, Rhinelander, WI, United States.
Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2018 Jul - Aug; Vol. 92, pp. 43-51. Date of Electronic Publication: 2018 Mar 02.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-488X
DOI:10.1016/j.vascn.2018.02.009