The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs.
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| Title: | The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs. |
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| Authors: | Chiang AY; Eli Lilly and Company, Indianapolis, IN, United States., Guth BD; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany; The Preclinical Drug Development Platform, North-West University, Potchefstroom, South Africa., Pugsley MK; Purdue Pharma, LP, Stamford, CT, United States., Foley CM; AbbVie, Abbott Park, IL, United States., Doyle JM; Data Sciences International, St. Paul, MN, United States., Engwall MJ; Amgen, Thousand Oaks, CA, United States., Koerner JE; FDA, Washington DC, United States., Parish ST; HESI, Washington DC, United States. Electronic address: sparish@hesiglobal.org., Dustan Sarazan R; Independent, Rhinelander, WI, United States. |
| Source: | Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2018 Jul - Aug; Vol. 92, pp. 43-51. Date of Electronic Publication: 2018 Mar 02. |
| Publication Type: | Journal Article; Multicenter Study |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1873-488X |
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| DOI: | 10.1016/j.vascn.2018.02.009 |