The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors.
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| Title: | The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors. |
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| Authors: | Pham HT; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada., Labrie L; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada., Wijting IEA; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands., Hassounah S; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada., Lok KY; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada., Portna I; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada., Goring ME; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada., Han Y; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada., Lungu C; Department of Viroscience, Erasmus University, Rotterdam, Netherlands., van der Ende ME; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands., Brenner BG; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Faculty of Surgery, McGill University, Montreal, Canada., Boucher CA; Department of Viroscience, Erasmus University, Rotterdam, Netherlands., Rijnders BJA; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands., van Kampen JJA; Department of Viroscience, Erasmus University, Rotterdam, Netherlands., Mesplède T; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada., Wainberg MA; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada. |
| Source: | The Journal of infectious diseases [J Infect Dis] 2018 Jul 24; Vol. 218 (5), pp. 698-706. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 29617824 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Pham+HT%22">Pham HT</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Labrie+L%22">Labrie L</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Wijting+IEA%22">Wijting IEA</searchLink>; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Hassounah+S%22">Hassounah S</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Lok+KY%22">Lok KY</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Portna+I%22">Portna I</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Goring+ME%22">Goring ME</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Lungu+C%22">Lungu C</searchLink>; Department of Viroscience, Erasmus University, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Ende+ME%22">van der Ende ME</searchLink>; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Brenner+BG%22">Brenner BG</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Faculty of Surgery, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Boucher+CA%22">Boucher CA</searchLink>; Department of Viroscience, Erasmus University, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Rijnders+BJA%22">Rijnders BJA</searchLink>; Department of Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Kampen+JJA%22">van Kampen JJA</searchLink>; Department of Viroscience, Erasmus University, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Mesplède+T%22">Mesplède T</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Wainberg+MA%22">Wainberg MA</searchLink>; McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Canada.; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Canada. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220413675%22">The Journal of infectious diseases</searchLink> [J Infect Dis] 2018 Jul 24; Vol. 218 (5), pp. 698-706. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0413675 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1537-6613 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221899%22">00221899 </searchLink><i>NLM ISO Abbreviation: </i>J Infect Dis <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=29617824 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/infdis/jiy175 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 698 Titles: – TitleFull: The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pham HT – PersonEntity: Name: NameFull: Labrie L – PersonEntity: Name: NameFull: Wijting IEA – PersonEntity: Name: NameFull: Hassounah S – PersonEntity: Name: NameFull: Lok KY – PersonEntity: Name: NameFull: Portna I – PersonEntity: Name: NameFull: Goring ME – PersonEntity: Name: NameFull: Han Y – PersonEntity: Name: NameFull: Lungu C – PersonEntity: Name: NameFull: van der Ende ME – PersonEntity: Name: NameFull: Brenner BG – PersonEntity: Name: NameFull: Boucher CA – PersonEntity: Name: NameFull: Rijnders BJA – PersonEntity: Name: NameFull: van Kampen JJA – PersonEntity: Name: NameFull: Mesplède T – PersonEntity: Name: NameFull: Wainberg MA IsPartOfRelationships: – BibEntity: Dates: – D: 24 M: 07 Text: 2018 Jul 24 Type: published Y: 2018 Identifiers: – Type: issn-electronic Value: 1537-6613 Numbering: – Type: volume Value: 218 – Type: issue Value: 5 Titles: – TitleFull: The Journal of infectious diseases Type: main |
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