| Authors: |
Mahajan A; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. anubha@well.ox.ac.uk., Wessel J; Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Indiana University, Indianapolis, IN, USA., Willems SM; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA., Robertson NR; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Chu AY; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gan W; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kitajima H; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Taliun D; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Rayner NW; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Guo X; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Lu Y; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Division of Nephrology and Hypertension, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA., Jensen RA; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA., Hu Y; Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China., Huo S; Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China., Lohman KK; Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UK., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Prins BP; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Flannick J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Trubetskoy VV; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Kravic J; Department of Clinical Sciences, Diabetes, and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden., Kim YJ; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea., Rybin DV; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Großhadern, Ludwig-Maximilians-Universität, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Varga TV; Department of Clinical Sciences, Lund University Diabetes Centre, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden., Marten J; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Li J; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., An P; Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St. Louis, MO, USA., Ligthart S; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Malerba G; Section of Biology and Genetics, Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy., Demirkan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Tajes JF; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Wuttke M; Institute of Genetic Epidemiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lecoeur C; CNRS, UMR 8199, Lille University, Lille Pasteur Institute, Lille, France., Preuss M; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Highland HM; Human Genetics Center, University of Texas Graduate School of Biomedical Sciences at Houston, University of Texas Health Science Center at Houston, Houston, TX, USA., Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Liu DJ; Department of Public Health Sciences, Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Peloso GM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Afaq S; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Afzal S; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ahlqvist E; Department of Clinical Sciences, Diabetes, and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden., Almgren P; Department of Clinical Sciences, Hypertension, and Cardiovascular Disease, Lund University, Malmö, Sweden., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Bang LB; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Bertoni AG; Department of Epidemiology and Prevention, Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, USA., Bombieri C; Section of Biology and Genetics, Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brandslund I; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark., Brody JA; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA., Burtt NP; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Canouil M; CNRS, UMR 8199, Lille University, Lille Pasteur Institute, Lille, France., Chen YI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Cho YS; Department of Biomedical Science, Hallym University, Chuncheon, Republic of Korea., Christensen C; Medical Department, Lillebælt Hospital Vejle, Vejle, Denmark., Eastwood SV; Institute of Cardiovascular Science, University College London, London, UK., Eckardt KU; Department of Nephrology and Medical Intensive Care, Charité, University Medicine Berlin, Berlin, Germany., Fischer K; Estonian Genome Center, University of Tartu, Tartu, Estonia., Gambaro G; Institute of Internal and Geriatric Medicine, Università Cattolica del Sacro Cuore, Rome, Italy., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., de Haan HG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Hackinger S; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Hai Y; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Han S; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea., Tybjærg-Hansen A; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Hivert MF; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Isomaa B; Malmska Municipal Health Care Center and Hospital, Jakobstad, Finland.; Folkhälsan Research Centre, Helsinki, Finland., Jäger S; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Jørgensen ME; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; National Institute of Public Health, Southern Denmark University, Copenhagen, Denmark., Jørgensen T; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Research Centre for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark., Käräjämäki A; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.; Diabetes Center, Vaasa Health Care Center, Vaasa, Finland., Kim BJ; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea., Kim SS; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Endocrinology, Abdominal Center, Helsinki University Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland.; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Kovacs P; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kriebel J; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Kronenberg F; Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Läll K; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia., Lange LA; Department of Medicine, Division of Bioinformatics and Personalized Medicine, University of Colorado Denver, Aurora, CO, USA., Lee JJ; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Li H; Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China., Lin KH; Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu J; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology, and Research (A*STAR), Singapore, Singapore., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mamakou V; Dromokaiteio Psychiatric Hospital, National and Kapodistrian University of Athens, Athens, Greece., McKean-Cowdin R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Nadkarni G; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Neville M; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ntalla I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Rathmann W; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Rode L; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Schönherr S; Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Selvin E; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Small KS; Department of Twins Research and Genetic Epidemiology, King's College London, London, UK., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Taylor KD; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Thorand B; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Tin A; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Tönjes A; Department of Medicine, University of Leipzig, Leipzig, Germany., Varbo A; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Witte DR; Department of Public Health, Aarhus University, Aarhus, Denmark.; Danish Diabetes Academy, Odense, Denmark., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Yajnik P; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Yao J; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Yengo L; CNRS, UMR 8199, Lille University, Lille Pasteur Institute, Lille, France., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Amouyel P; Institut Pasteur de Lille, INSERM U1167, Université Lille Nord de France, Lille, France., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chowdhury R; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Collins FS; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Dedoussis G; Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Ferrario MM; Research Centre on Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Varese, Italy., Ferrières J; INSERM, UMR 1027, Toulouse, France.; Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France., Florez JC; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Frossard P; Center for Non-Communicable Diseases, Karachi, Pakistan., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA., Heckbert SR; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA., Howson JMM; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ingelsson M; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Kathiresan S; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Kee F; UKCRC Centre of Excellence for Public Health (NI), Queens University of Belfast, Belfast, UK., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA., Lindgren CM; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Big Data Institute, Li Ka Shing Centre For Health Information and Discovery, University of Oxford, Oxford, UK., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Meitinger T; Institute of Human Genetics, Technische Universität München, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Melander O; Department of Clinical Sciences, Hypertension, and Cardiovascular Disease, Lund University, Malmö, Sweden., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Moitry M; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.; Department of Public Health, University Hospital of Strasbourg, Strasbourg, France., Morris AD; Clinical Research Centre, Centre for Molecular Medicine, Ninewells Hospital and Medical School, Dundee, UK.; Usher Institute to the Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Murray AD; Aberdeen Biomedical Imaging Centre, School of Medicine, Medical Sciences, and Nutrition, University of Aberdeen, Aberdeen, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Orho-Melander M; Department of Clinical Sciences, Diabetes, and Cardiovascular Disease, Genetic Epidemiology, Lund University, Malmö, Sweden., Owen KR; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Perola M; National Institute for Health and Welfare, Helsinki, Finland.; Finnish Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland., Peters A; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Province MA; Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St. Louis, MO, USA., Rasheed A; Center for Non-Communicable Diseases, Karachi, Pakistan., Ridker PM; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Rivadineira F; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Rosengren AH; Department of Clinical Sciences, Diabetes, and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Sheu WH; Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; National Yang-Ming University, School of Medicine, Taipei, Taiwan.; National Defense Medical Center, School of Medicine, Taipei, Taiwan., Sladek R; McGill University and Génome Québec Innovation Centre, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McGill University, Montreal, QC, Canada., Smith BH; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry, and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Uitterlinden AG; Department of Medical Sciences, Molecular Epidemiology, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Varma R; USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Blüher M; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK., Chasman DI; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.; British Heart Foundation, Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., van Duijn C; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Dupuis J; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Franks PW; Department of Clinical Sciences, Lund University Diabetes Centre, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA., Froguel P; CNRS, UMR 8199, Lille University, Lille Pasteur Institute, Lille, France.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, UK., Grallert H; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Clinical Cooperation Group Type 2 Diabetes, Helmholtz Zentrum München, Ludwig-Maximillians University Munich, Munich, Germany.; Clinical Cooperation Group Nutrigenomics and Type 2 Diabetes, Helmholtz Zentrum München, Technical University of Munich, Munich, Germany., Groop L; Department of Clinical Sciences, Diabetes, and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Finnish Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland., Han BG; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Ingelsson E; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medical Sciences, Molecular Epidemiology, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kooner JS; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; National Heart and Lung Institute, Cardiovascular Sciences, Hammersmith Campus, Imperial College London, London, UK., Köttgen A; Institute of Genetic Epidemiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Kuulasmaa K; Institute of Human Genetics, Technische Universität München, Munich, Germany., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lin X; Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Liu Y; Department of Epidemiology and Prevention, Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, USA., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Marchini J; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Statistics, University of Oxford, Oxford, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mook-Kanamori D; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Rauramaa R; Foundation for Research in Health, Exercise, and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Sattar N; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Schulze MB; 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