In vitro and in vivo characterization of an interleukin-15 antagonist peptide by metabolic stability, 99m Tc-labeling, and biological activity assays.

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Title: In vitro and in vivo characterization of an interleukin-15 antagonist peptide by metabolic stability, 99m Tc-labeling, and biological activity assays.
Authors: Rodríguez-Álvarez Y; Pharmaceutical Department, Center for Genetic Engineering and Biotechnology, Avenue 31, PO Box 6162, Havana, 10600, Cuba., Cabrales-Rico A; Chemistry and Physics Department, Center for Genetic Engineering and Biotechnology, Avenue 31, PO Box 6162, Havana, 10600, Cuba., Perera-Pintado A; Center for Clinical Research, Avenue 34, PO Box 6162, Havana, 11300, Cuba., Prats-Capote A; Center for Clinical Research, Avenue 34, PO Box 6162, Havana, 11300, Cuba., Garay-Pérez HE; Chemistry and Physics Department, Center for Genetic Engineering and Biotechnology, Avenue 31, PO Box 6162, Havana, 10600, Cuba., Reyes-Acosta O; Chemistry and Physics Department, Center for Genetic Engineering and Biotechnology, Avenue 31, PO Box 6162, Havana, 10600, Cuba., Pérez-García E; Pharmaceutical Department, Center for Genetic Engineering and Biotechnology, Avenue 31, PO Box 6162, Havana, 10600, Cuba., Chico-Capote A; Rheumatology Department, Hermanos Ameijeiras Hospital, San Lazaro 701, PO Box 6122, Havana, 10600, Cuba., Santos-Savio A; Pharmaceutical Department, Center for Genetic Engineering and Biotechnology, Avenue 31, PO Box 6162, Havana, 10600, Cuba.
Source: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2018 Jun; Vol. 24 (4-5), pp. e3078. Date of Electronic Publication: 2018 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9506309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1387 (Electronic) Linking ISSN: 10752617 NLM ISO Abbreviation: J Pept Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1099-1387
DOI:10.1002/psc.3078