Evaluation of the Efficacy, Safety, and Tolerability of BI 409306, a Novel Phosphodiesterase 9 Inhibitor, in Cognitive Impairment in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial.
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| Title: | Evaluation of the Efficacy, Safety, and Tolerability of BI 409306, a Novel Phosphodiesterase 9 Inhibitor, in Cognitive Impairment in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial. |
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| Authors: | Brown D; Community Clinical Research, Inc, Austin, TX., Nakagome K; Department of Forensic Psychiatry, National Center of Neurology and Psychiatry, Kodaira, Japan., Cordes J; Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany., Brenner R; Neurobehavioral Research, Inc, New York, NY., Gründer G; Department of Molecular Neuroimaging, Central Institute of Mental Health, Clinical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Keefe RSE; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC., Riesenberg R; Atlanta Center for Medical Research, Atlanta, GA., Walling DP; CNS Network, Inc, Garden Grove, CA., Daniels K; Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT., Wang L; Boehringer Ingelheim Taiwan Limited, Taipei, Taiwan., McGinniss J; Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT., Sand M; Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT. |
| Source: | Schizophrenia bulletin [Schizophr Bull] 2019 Mar 07; Vol. 45 (2), pp. 350-359. |
| Publication Type: | Adaptive Clinical Trial; Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0236760 Publication Model: Print Cited Medium: Internet ISSN: 1745-1701 (Electronic) Linking ISSN: 05867614 NLM ISO Abbreviation: Schizophr Bull Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 29718385 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Evaluation of the Efficacy, Safety, and Tolerability of BI 409306, a Novel Phosphodiesterase 9 Inhibitor, in Cognitive Impairment in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Brown+D%22">Brown D</searchLink>; Community Clinical Research, Inc, Austin, TX.<br /><searchLink fieldCode="AU" term="%22Nakagome+K%22">Nakagome K</searchLink>; Department of Forensic Psychiatry, National Center of Neurology and Psychiatry, Kodaira, Japan.<br /><searchLink fieldCode="AU" term="%22Cordes+J%22">Cordes J</searchLink>; Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Brenner+R%22">Brenner R</searchLink>; Neurobehavioral Research, Inc, New York, NY.<br /><searchLink fieldCode="AU" term="%22Gründer+G%22">Gründer G</searchLink>; Department of Molecular Neuroimaging, Central Institute of Mental Health, Clinical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Keefe+RSE%22">Keefe RSE</searchLink>; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Riesenberg+R%22">Riesenberg R</searchLink>; Atlanta Center for Medical Research, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Walling+DP%22">Walling DP</searchLink>; CNS Network, Inc, Garden Grove, CA.<br /><searchLink fieldCode="AU" term="%22Daniels+K%22">Daniels K</searchLink>; Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Boehringer Ingelheim Taiwan Limited, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22McGinniss+J%22">McGinniss J</searchLink>; Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT.<br /><searchLink fieldCode="AU" term="%22Sand+M%22">Sand M</searchLink>; Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220236760%22">Schizophrenia bulletin</searchLink> [Schizophr Bull] 2019 Mar 07; Vol. 45 (2), pp. 350-359. – Name: TypePub Label: Publication Type Group: TypPub Data: Adaptive Clinical Trial; Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0236760 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-1701 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2205867614%22">05867614 </searchLink><i>NLM ISO Abbreviation: </i>Schizophr Bull <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=29718385 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/schbul/sby049 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 350 Titles: – TitleFull: Evaluation of the Efficacy, Safety, and Tolerability of BI 409306, a Novel Phosphodiesterase 9 Inhibitor, in Cognitive Impairment in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Brown D – PersonEntity: Name: NameFull: Nakagome K – PersonEntity: Name: NameFull: Cordes J – PersonEntity: Name: NameFull: Brenner R – PersonEntity: Name: NameFull: Gründer G – PersonEntity: Name: NameFull: Keefe RSE – PersonEntity: Name: NameFull: Riesenberg R – PersonEntity: Name: NameFull: Walling DP – PersonEntity: Name: NameFull: Daniels K – PersonEntity: Name: NameFull: Wang L – PersonEntity: Name: NameFull: McGinniss J – PersonEntity: Name: NameFull: Sand M IsPartOfRelationships: – BibEntity: Dates: – D: 07 M: 03 Text: 2019 Mar 07 Type: published Y: 2019 Identifiers: – Type: issn-electronic Value: 1745-1701 Numbering: – Type: volume Value: 45 – Type: issue Value: 2 Titles: – TitleFull: Schizophrenia bulletin Type: main |
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