Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.
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| Title: | Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. |
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| Authors: | Pardi N; Department of Medicine, University of Pennsylvania, Philadelphia, PA pnorbert@pennmedicine.upenn.edu., Hogan MJ; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Naradikian MS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Parkhouse K; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Jones L; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Moody MA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Verkerke HP; Department of Medicinal Chemistry, University of Washington, Seattle, WA., Myles A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Willis E; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC., Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC., Lobby JL; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Liao HX; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Korber BT; Los Alamos National Laboratory, Los Alamos, NM., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Scearce RM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Hraber PT; Los Alamos National Laboratory, Los Alamos, NM., Tombácz I; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Muramatsu H; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Ni H; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Balikov DA; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Li C; Department of Medicine, University of Pennsylvania, Philadelphia, PA., Mui BL; Acuitas Therapeutics, Vancouver, BC, Canada., Tam YK; Acuitas Therapeutics, Vancouver, BC, Canada., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY., Karikó K; BioNTech RNA Pharmaceuticals, Mainz, Germany., Polacino P; Washington National Primate Research Center, University of Washington, Seattle, WA., Eisenlohr LC; Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA., Madden TD; Acuitas Therapeutics, Vancouver, BC, Canada., Hope MJ; Acuitas Therapeutics, Vancouver, BC, Canada., Lewis MG; Bioqual Inc., Rockville, MD., Lee KK; Department of Medicinal Chemistry, University of Washington, Seattle, WA., Hu SL; Washington National Primate Research Center, University of Washington, Seattle, WA.; Department of Pharmaceutics, University of Washington, Seattle, WA., Hensley SE; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Cancro MP; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC., Weissman D; Department of Medicine, University of Pennsylvania, Philadelphia, PA dreww@pennmedicine.upenn.edu. |
| Source: | The Journal of experimental medicine [J Exp Med] 2018 Jun 04; Vol. 215 (6), pp. 1571-1588. Date of Electronic Publication: 2018 May 08. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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