Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.

Saved in:
Bibliographic Details
Title: Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
Authors: Burvenich IJG; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Farrugia W; Burnet Institute, Melbourne, VIC, Australia., Liu Z; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Makris D; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., King D; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Gloria B; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Perani A; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Allan LC; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Scott AM; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Molecular Imaging and Therapy, Austin Health, University of Melbourne, Melbourne, Australia.; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia., Ramsland PA; Burnet Institute, Melbourne, VIC, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Science, RMIT University, Bundoora, VIC, Australia.; Department of Immunology, Monash University, Melbourne, VIC, Australia.; Department of Surgery Austin Health, University of Melbourne, Heidelberg, VIC, Australia.
Source: The Biochemical journal [Biochem J] 2018 Jul 05; Vol. 475 (13), pp. 2179-2190. Date of Electronic Publication: 2018 Jul 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Electronic Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1470-8728
DOI:10.1042/BCJ20180139