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Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.

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Title: Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
Authors: Burvenich IJG; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Farrugia W; Burnet Institute, Melbourne, VIC, Australia., Liu Z; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Makris D; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., King D; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Gloria B; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Perani A; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Allan LC; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Scott AM; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Molecular Imaging and Therapy, Austin Health, University of Melbourne, Melbourne, Australia.; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia., Ramsland PA; Burnet Institute, Melbourne, VIC, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Science, RMIT University, Bundoora, VIC, Australia.; Department of Immunology, Monash University, Melbourne, VIC, Australia.; Department of Surgery Austin Health, University of Melbourne, Heidelberg, VIC, Australia.
Source: The Biochemical journal [Biochem J] 2018 Jul 05; Vol. 475 (13), pp. 2179-2190. Date of Electronic Publication: 2018 Jul 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Electronic Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
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  Data: <searchLink fieldCode="AU" term="%22Burvenich+IJG%22">Burvenich IJG</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Farrugia+W%22">Farrugia W</searchLink>; Burnet Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Makris+D%22">Makris D</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22King+D%22">King D</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Gloria+B%22">Gloria B</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Perani+A%22">Perani A</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Allan+LC%22">Allan LC</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Scott+AM%22">Scott AM</searchLink>; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Molecular Imaging and Therapy, Austin Health, University of Melbourne, Melbourne, Australia.; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ramsland+PA%22">Ramsland PA</searchLink>; Burnet Institute, Melbourne, VIC, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Science, RMIT University, Bundoora, VIC, Australia.; Department of Immunology, Monash University, Melbourne, VIC, Australia.; Department of Surgery Austin Health, University of Melbourne, Heidelberg, VIC, Australia.
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  Data: <searchLink fieldCode="JN" term="%222984726R%22">The Biochemical journal</searchLink> [Biochem J] 2018 Jul 05; Vol. 475 (13), pp. 2179-2190. <i>Date of Electronic Publication: </i>2018 Jul 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Published+by+Portland+Press+on+behalf+of+the+Biochemical+Society%22">Published by Portland Press on behalf of the Biochemical Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2984726R <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1470-8728 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202646021%22">02646021 </searchLink><i>NLM ISO Abbreviation: </i>Biochem J <i>Subsets: </i>MEDLINE
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              Text: 2018 Jul 05
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