Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
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| Title: | Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions. |
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| Authors: | Burvenich IJG; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Farrugia W; Burnet Institute, Melbourne, VIC, Australia., Liu Z; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Makris D; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., King D; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Gloria B; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Perani A; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Allan LC; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Scott AM; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Molecular Imaging and Therapy, Austin Health, University of Melbourne, Melbourne, Australia.; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia., Ramsland PA; Burnet Institute, Melbourne, VIC, Australia paul.ramsland@rmit.edu.au andrew.scott@onjcri.org.au.; School of Science, RMIT University, Bundoora, VIC, Australia.; Department of Immunology, Monash University, Melbourne, VIC, Australia.; Department of Surgery Austin Health, University of Melbourne, Heidelberg, VIC, Australia. |
| Source: | The Biochemical journal [Biochem J] 2018 Jul 05; Vol. 475 (13), pp. 2179-2190. Date of Electronic Publication: 2018 Jul 05. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Electronic Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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