Melanoma response to anti-PD-L1 immunotherapy requires JAK1 signaling, but not JAK2.

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Title: Melanoma response to anti-PD-L1 immunotherapy requires JAK1 signaling, but not JAK2.
Authors: Luo N; Department of Anatomy and Histology, School of Medicine, Nankai University, Tianjin, China.; Departments of Medicine, Vanderbilt University Medical Center, Nashville TN, USA., Formisano L; Departments of Medicine, Vanderbilt University Medical Center, Nashville TN, USA., Gonzalez-Ericsson PI; Breast Cancer Research Program, Vanderbilt University Medical Center, Nashville TN, USA., Sanchez V; Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville TN, USA., Dean PT; Departments of Medicine, Vanderbilt University Medical Center, Nashville TN, USA., Opalenik SR; Departments of Medicine, Vanderbilt University Medical Center, Nashville TN, USA., Sanders ME; Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville TN, USA., Cook RS; Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville TN, USA.; Cancer Biology Program, Vanderbilt University Medical Center, Nashville TN, USA.; Breast Cancer Research Program, Vanderbilt University Medical Center, Nashville TN, USA.; Department of Biomedical Engineering, Vanderbilt University Medical Center, Nashville TN., Arteaga CL; Departments of Medicine, Vanderbilt University Medical Center, Nashville TN, USA.; Department of Biomedical Engineering, Vanderbilt University Medical Center, Nashville TN., Johnson DB; Departments of Medicine, Vanderbilt University Medical Center, Nashville TN, USA., Balko JM; Departments of Medicine, Vanderbilt University Medical Center, Nashville TN, USA.; Cancer Biology Program, Vanderbilt University Medical Center, Nashville TN, USA.; Breast Cancer Research Program, Vanderbilt University Medical Center, Nashville TN, USA.
Source: Oncoimmunology [Oncoimmunology] 2018 Mar 06; Vol. 7 (6), pp. e1438106. Date of Electronic Publication: 2018 Mar 06 (Print Publication: 2018).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: eCollection Cited Medium: Print ISSN: 2162-4011 (Print) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2162-4011
DOI:10.1080/2162402X.2018.1438106