Targeting Serotonin 2A and Adrenergic α1 Receptors for Ocular Antihypertensive Agents: Discovery of 3,4-Dihydropyrazino[1,2-b]indazol-1(2H)-one Derivatives.
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| Title: | Targeting Serotonin 2A and Adrenergic α |
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| Authors: | Furlotti G; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy., Alisi MA; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy., Cazzolla N; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy., Ceccacci F; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.; Current affiliation: Istituto di Metodologie Chimiche-CNR, Unità Organizzativa di Supporto, Sede di Roma, Università degli Studi di Roma 'La Sapienza', P. le Aldo Moro 5, 00185, Rome, Italy)., Garrone B; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy., Gasperi T; Department of Science, Section of Nanoscience and Nanotechnology, University of Roma Tre, via della Vasca Navale 79, 00146, Rome, Italy., La Bella A; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy., Leonelli F; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.; Dipartimento di Biologia Ambientale, University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy., Loreto MA; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy., Magarò G; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy., Mangano G; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy., Bettolo RM; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy., Masini E; Departments of NEUROFARBA, Section of Pharmacology, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy., Miceli M; Department of Science, Section of Nanoscience and Nanotechnology, University of Roma Tre, via della Vasca Navale 79, 00146, Rome, Italy., Migneco LM; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy., Vitiello M; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy. |
| Source: | ChemMedChem [ChemMedChem] 2018 Aug 10; Vol. 13 (15), pp. 1597-1607. Date of Electronic Publication: 2018 Jul 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 29873449 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Targeting Serotonin 2A and Adrenergic α<subscript>1</subscript> Receptors for Ocular Antihypertensive Agents: Discovery of 3,4-Dihydropyrazino[1,2-b]indazol-1(2H)-one Derivatives. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Furlotti+G%22">Furlotti G</searchLink>; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy.<br /><searchLink fieldCode="AU" term="%22Alisi+MA%22">Alisi MA</searchLink>; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy.<br /><searchLink fieldCode="AU" term="%22Cazzolla+N%22">Cazzolla N</searchLink>; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy.<br /><searchLink fieldCode="AU" term="%22Ceccacci+F%22">Ceccacci F</searchLink>; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.; Current affiliation: Istituto di Metodologie Chimiche-CNR, Unità Organizzativa di Supporto, Sede di Roma, Università degli Studi di Roma 'La Sapienza', P. le Aldo Moro 5, 00185, Rome, Italy).<br /><searchLink fieldCode="AU" term="%22Garrone+B%22">Garrone B</searchLink>; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy.<br /><searchLink fieldCode="AU" term="%22Gasperi+T%22">Gasperi T</searchLink>; Department of Science, Section of Nanoscience and Nanotechnology, University of Roma Tre, via della Vasca Navale 79, 00146, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22La+Bella+A%22">La Bella A</searchLink>; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Leonelli+F%22">Leonelli F</searchLink>; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.; Dipartimento di Biologia Ambientale, University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Loreto+MA%22">Loreto MA</searchLink>; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Magarò+G%22">Magarò G</searchLink>; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy.<br /><searchLink fieldCode="AU" term="%22Mangano+G%22">Mangano G</searchLink>; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy.<br /><searchLink fieldCode="AU" term="%22Bettolo+RM%22">Bettolo RM</searchLink>; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Masini+E%22">Masini E</searchLink>; Departments of NEUROFARBA, Section of Pharmacology, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Miceli+M%22">Miceli M</searchLink>; Department of Science, Section of Nanoscience and Nanotechnology, University of Roma Tre, via della Vasca Navale 79, 00146, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Migneco+LM%22">Migneco LM</searchLink>; Chemistry Department 'S. Cannizzaro', University of Rome 'La Sapienza', P.le Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Vitiello+M%22">Vitiello M</searchLink>; Angelini RR&D (Research, Regulatory & Development), Angelini S.p.A., Piazzale della stazione snc, 00071, S. Palomba-Pomezia (Rome), Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101259013%22">ChemMedChem</searchLink> [ChemMedChem] 2018 Aug 10; Vol. 13 (15), pp. 1597-1607. <i>Date of Electronic Publication: </i>2018 Jul 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-VCH%22">Wiley-VCH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101259013 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1860-7187 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218607179%22">18607179 </searchLink><i>NLM ISO Abbreviation: </i>ChemMedChem |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=29873449 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/cmdc.201800199 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1597 Titles: – TitleFull: Targeting Serotonin 2A and Adrenergic α1 Receptors for Ocular Antihypertensive Agents: Discovery of 3,4-Dihydropyrazino[1,2-b]indazol-1(2H)-one Derivatives. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Furlotti G – PersonEntity: Name: NameFull: Alisi MA – PersonEntity: Name: NameFull: Cazzolla N – PersonEntity: Name: NameFull: Ceccacci F – PersonEntity: Name: NameFull: Garrone B – PersonEntity: Name: NameFull: Gasperi T – PersonEntity: Name: NameFull: La Bella A – PersonEntity: Name: NameFull: Leonelli F – PersonEntity: Name: NameFull: Loreto MA – PersonEntity: Name: NameFull: Magarò G – PersonEntity: Name: NameFull: Mangano G – PersonEntity: Name: NameFull: Bettolo RM – PersonEntity: Name: NameFull: Masini E – PersonEntity: Name: NameFull: Miceli M – PersonEntity: Name: NameFull: Migneco LM – PersonEntity: Name: NameFull: Vitiello M IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 08 Text: 2018 Aug 10 Type: published Y: 2018 Identifiers: – Type: issn-electronic Value: 1860-7187 Numbering: – Type: volume Value: 13 – Type: issue Value: 15 Titles: – TitleFull: ChemMedChem Type: main |
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