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An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.

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Title: An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.
Authors: Galarza Torre A; Wellcome Centre for Cell-Matrix Research, University of Manchester, Manchester, M13 9PT, UK.; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, University of Manchester, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK.; Scottish Centre for Regenerative Medicine, Edinburgh, EH16 4UU, UK., Shaw JE; Wellcome Centre for Cell-Matrix Research, University of Manchester, Manchester, M13 9PT, UK.; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, University of Manchester, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK., Wood A; Division of Cancer Sciences, School of Medical Sciences, University of Manchester, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK., Gilbert HTJ; Wellcome Centre for Cell-Matrix Research, University of Manchester, Manchester, M13 9PT, UK.; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, University of Manchester, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK., Dobre O; Wellcome Centre for Cell-Matrix Research, University of Manchester, Manchester, M13 9PT, UK.; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, University of Manchester, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK.; School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK., Genever P; Department of Biology, University of York, York, YO10 5DD, UK., Brennan K; Division of Cancer Sciences, School of Medical Sciences, University of Manchester, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK., Richardson SM; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, University of Manchester, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK., Swift J; Wellcome Centre for Cell-Matrix Research, University of Manchester, Manchester, M13 9PT, UK. joe.swift@manchester.ac.uk.; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, University of Manchester, Manchester, UK. joe.swift@manchester.ac.uk.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK. joe.swift@manchester.ac.uk.
Source: Scientific reports [Sci Rep] 2018 Jun 12; Vol. 8 (1), pp. 8981. Date of Electronic Publication: 2018 Jun 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-018-27346-9