Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas.
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| Title: | Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas. |
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| Authors: | Saenz-Ponce N; Epithelial Pathobiology Group, University of Queensland Diamantina Institute, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland 4102, Australia., Pillay R; Epithelial Pathobiology Group, University of Queensland Diamantina Institute, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland 4102, Australia., de Long LM; Epithelial Pathobiology Group, University of Queensland Diamantina Institute, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland 4102, Australia., Kashyap T; Karyopharm Therapeutics Inc., Newton, MA 02459, USA., Argueta C; Karyopharm Therapeutics Inc., Newton, MA 02459, USA., Landesman Y; Karyopharm Therapeutics Inc., Newton, MA 02459, USA., Hazar-Rethinam M; Massachusetts General Hospital Cancer Center, Harvard Medical School, MA 02114, USA., Boros S; Department of Pathology, Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia., Panizza B; Department of Ear Nose and Throat, Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia.; School of Medicine, University of Queensland, Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia., Jacquemyn M; Katholieke Universiteit Leuven, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Herestraat 49, 3000 Leuven, Belgium., Daelemans D; Katholieke Universiteit Leuven, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Herestraat 49, 3000 Leuven, Belgium., Gannon OM; Epithelial Pathobiology Group, University of Queensland Diamantina Institute, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland 4102, Australia., Saunders NA; Epithelial Pathobiology Group, University of Queensland Diamantina Institute, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland 4102, Australia. nsaunders@uq.edu.au. |
| Source: | Science translational medicine [Sci Transl Med] 2018 Jun 27; Vol. 10 (447). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.aar7223 |
