The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort.
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| Title: | The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort. |
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| Authors: | Tariot PN; Banner Alzheimer's Institute, Phoenix, AZ, USA., Lopera F; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Langbaum JB; Banner Alzheimer's Institute, Phoenix, AZ, USA., Thomas RG; Department of Neurosciences, University of California San Diego School of Medicine, La Jolla, CA, USA., Hendrix S; Pentara Corporation, Salt Lake City, UT, USA., Schneider LS; USC State of California Alzheimer's Disease Research and Clinical Center, Keck Medicine of USC, Los Angeles, CA, USA., Rios-Romenets S; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Giraldo M; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Acosta N; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Tobon C; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Ramos C; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Espinosa A; Grupo de Neurociencias, Universidad de Antioquia, SIU, Medellín, Colombia., Cho W; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Ward M; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Clayton D; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Friesenhahn M; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Mackey H; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Honigberg L; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Sanabria Bohorquez S; Genentech, a Member of the Roche Group, South San Francisco, CA, USA., Chen K; Banner Alzheimer's Institute, Phoenix, AZ, USA., Walsh T; Banner Alzheimer's Institute, Phoenix, AZ, USA., Langlois C; Banner Alzheimer's Institute, Phoenix, AZ, USA., Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA. |
| Corporate Authors: | Alzheimer's Prevention Initiative |
| Source: | Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2018 Mar 08; Vol. 4, pp. 150-160. Date of Electronic Publication: 2018 Mar 08 (Print Publication: 2018). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2352-8737 |
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| DOI: | 10.1016/j.trci.2018.02.002 |
