Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.

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Bibliographic Details
Title: Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.
Authors: Lenting K; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., Khurshed M; Department of Medical Biology, Cancer Center Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands., Peeters TH; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., van den Heuvel CNAM; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., van Lith SAM; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., de Bitter T; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., Hendriks W; Department of Cell Biology, Radboud Institute of Molecular Life Sciences, Nijmegen, The Netherlands., Span PN; Radiotherapy and Oncoimmunology Laboratory, Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands., Molenaar RJ; Department of Medical Biology, Cancer Center Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands., Botman D; Department of Medical Biology, Cancer Center Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands., Verrijp K; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., Heerschap A; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., Ter Laan M; Department of Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands; and., Kusters B; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., van Ewijk A; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Huynen MA; Center for Molecular and Biomolecular Informatics, Radboud Institute of Molecular Life Sciences, Nijmegen, The Netherlands., van Noorden CJF; Department of Medical Biology, Cancer Center Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands., Leenders WPJ; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Jan; Vol. 33 (1), pp. 557-571. Date of Electronic Publication: 2018 Jul 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1530-6860
DOI:10.1096/fj.201800907RR