Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.
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| Title: | Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy. |
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| Authors: | Lawrence MG; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Melbourne Urological Research Alliance (MURAL), Melbourne, VIC, Australia., Obinata D; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Sandhu S; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Cancer Tissue Collection After Death (CASCADE) Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Selth LA; Dame Roma Mitchell Cancer Research Laboratories and Freemasons Foundation Centre for Men's Health, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Wong SQ; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Molecular Biomarkers and Translational Genomics Lab, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Porter LH; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Lister N; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Pook D; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Medical Oncology, Monash Health, Clayton, VIC, Australia., Pezaro CJ; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Eastern Health and Monash University Eastern Health Clinical School, Box Hill, VIC, Australia., Goode DL; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Rebello RJ; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Clark AK; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Papargiris M; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Melbourne Urological Research Alliance (MURAL), Melbourne, VIC, Australia; Australian Prostate Cancer Bioresource, VIC Node, Monash University, Clayton, VIC, Australia., Van Gramberg J; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Australian Prostate Cancer Bioresource, VIC Node, Monash University, Clayton, VIC, Australia., Hanson AR; Dame Roma Mitchell Cancer Research Laboratories and Freemasons Foundation Centre for Men's Health, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Banks P; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Wang H; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Niranjan B; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Keerthikumar S; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Hedwards S; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Huglo A; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Yang R; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA., Henzler C; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA., Li Y; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Lopez-Campos F; Spanish National Cancer Research Centre, Madrid, Spain., Castro E; Spanish National Cancer Research Centre, Madrid, Spain., Toivanen R; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Azad A; Medical Oncology, Monash Health, Clayton, VIC, Australia; Department of Medicine, School of Clinical Sciences, Monash University, Clayton, VIC, Australia., Bolton D; Department of Urology, Austin Hospital, The University of Melbourne, Melbourne Heidelberg, VIC, Australia; Department of Surgery, The University of Melbourne, Parkville, VIC, Australia., Goad J; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia., Grummet J; Epworth Healthcare, Melbourne, VIC, Australia; Department of Surgery, Central Clinical School, Monash University, Clayton, VIC, Australia; Australian Urology Associates, Melbourne, VIC, Australia., Harewood L; Department of Surgery, The University of Melbourne, Parkville, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia., Kourambas J; Department of Medicine, Monash Health, Casey Hospital, Berwick, VIC, Australia., Lawrentschuk N; Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC, Australia; Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, VIC, Australia., Moon D; Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia; Australian Urology Associates, Melbourne, VIC, Australia; Central Clinical School, Monash University, Clayton, VIC, Australia; The Epworth Prostate Centre, Epworth Hospital, Richmond, VIC, Australia., Murphy DG; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia., Sengupta S; Eastern Health and Monash University Eastern Health Clinical School, Box Hill, VIC, Australia; Department of Urology, Austin Hospital, The University of Melbourne, Melbourne Heidelberg, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia; Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, VIC, Australia; Epworth Freemasons, Epworth Health, East Melbourne, VIC, Australia., Snow R; Australian Urology Associates, Melbourne, VIC, Australia., Thorne H; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; kConFab, Research Department, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Mitchell C; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Pedersen J; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; TissuPath, Mount Waverley, VIC, Australia., Clouston D; TissuPath, Mount Waverley, VIC, Australia., Norden S; TissuPath, Mount Waverley, VIC, Australia., Ryan A; TissuPath, Mount Waverley, VIC, Australia., Dehm SM; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; Departments of Laboratory Medicine and Pathology and Urology, University of Minnesota, Minneapolis, MN, USA., Tilley WD; Dame Roma Mitchell Cancer Research Laboratories and Freemasons Foundation Centre for Men's Health, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Pearson RB; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, VIC, Australia; Oncogenic Signaling and Growth Control Program, Cancer Research Division, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia., Hannan RD; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, VIC, Australia; Oncogenic Signaling and Growth Control Program, Cancer Research Division, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia; ACRF Department of Cancer Biology and Therapeutics, John Curtin School of Medical Research, Australian National University, ACT, Australia., Frydenberg M; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Epworth Healthcare, Melbourne, VIC, Australia; Australian Urology Associates, Melbourne, VIC, Australia; Department of Surgery, Monash University, Clayton, VIC, Australia., Furic L; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Taylor RA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Melbourne Urological Research Alliance (MURAL), Melbourne, VIC, Australia; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Physiology, Monash University, Clayton, VIC, Australia., Risbridger GP; Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Melbourne Urological Research Alliance (MURAL), Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia. Electronic address: gail.risbridger@monash.edu. |
| Source: | European urology [Eur Urol] 2018 Nov; Vol. 74 (5), pp. 562-572. Date of Electronic Publication: 2018 Jul 23. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Science Country of Publication: Switzerland NLM ID: 7512719 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7560 (Electronic) Linking ISSN: 03022838 NLM ISO Abbreviation: Eur Urol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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