A long-term culture system based on a collagen vitrigel membrane chamber that supports liver-specific functions of hepatocytes isolated from mice with humanized livers.

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Title:	A long-term culture system based on a collagen vitrigel membrane chamber that supports liver-specific functions of hepatocytes isolated from mice with humanized livers.
Authors:	Watari R; Drug Metabolism and Pharmacokinetics Tsukuba, Global Drug Metabolism and Pharmacokinetics, Biopharmaceutical Assessments Core Function Unit, Medicine Development Center, Eisai Co., Ltd.; Department of Genomics-Based Drug Discovery, Graduate School of Comprehensive Human Sciences, University of Tsukuba., Kakiki M; Drug Metabolism and Pharmacokinetics Tsukuba, Global Drug Metabolism and Pharmacokinetics, Biopharmaceutical Assessments Core Function Unit, Medicine Development Center, Eisai Co., Ltd., Oshikata A; Division of Biotechnology, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization., Takezawa T; Division of Biotechnology, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization., Yamasaki C; R&D Department, PhoenixBio Co., Ltd., Ishida Y; R&D Department, PhoenixBio Co., Ltd., Tateno C; R&D Department, PhoenixBio Co., Ltd., Kuroda Y; Division of Pharmacology, National Institute of Health Sciences., Ishida S; Division of Pharmacology, National Institute of Health Sciences., Kusano K; Drug Metabolism and Pharmacokinetics Tsukuba, Global Drug Metabolism and Pharmacokinetics, Biopharmaceutical Assessments Core Function Unit, Medicine Development Center, Eisai Co., Ltd.
Source:	The Journal of toxicological sciences [J Toxicol Sci] 2018; Vol. 43 (8), pp. 521-529.
Publication Type:	Journal Article
Journal Info:	Publisher: Doku Sayō Kenkyūkai Country of Publication: Japan NLM ID: 7805798 Publication Model: Print Cited Medium: Internet ISSN: 1880-3989 (Electronic) Linking ISSN: 03881350 NLM ISO Abbreviation: J Toxicol Sci Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1880-3989
DOI:	10.2131/jts.43.521