S-Nitrosylation of Divalent Metal Transporter 1 Enhances Iron Uptake to Mediate Loss of Dopaminergic Neurons and Motoric Deficit.

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Title: S-Nitrosylation of Divalent Metal Transporter 1 Enhances Iron Uptake to Mediate Loss of Dopaminergic Neurons and Motoric Deficit.
Authors: Liu C; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Zhang CW; Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, Nanjing 211816, People's Republic of China.; Department of Research, National Neuroscience Institute, Singapore 308433., Lo SQ; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Ang ST; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Chew KCM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597.; Department of Research, National Neuroscience Institute, Singapore 308433., Yu D; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Chai BH; Department of Research, National Neuroscience Institute, Singapore 308433., Tan B; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Tsang F; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597.; Department of Research, National Neuroscience Institute, Singapore 308433., Tai YK; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228., Tan BWQ; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Liang MC; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Tan HT; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596., Tang JY; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597., Lai MKP; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599., Chua JJE; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597.; Neurobiology and Ageing Programme, Life Sciences Institute, Centre for Life Sciences, National University of Singapore, Singapore 117456.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore 138673., Chung MCM; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596., Khanna S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597.; Neurobiology and Ageing Programme, Life Sciences Institute, Centre for Life Sciences, National University of Singapore, Singapore 117456., Lim KL; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597.; Department of Research, National Neuroscience Institute, Singapore 308433.; Neurobiology and Ageing Programme, Life Sciences Institute, Centre for Life Sciences, National University of Singapore, Singapore 117456.; Neuroscience and Behavioral Disorders Program, Duke-NUS Medical School, Singapore 169857, and., Soong TW; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, phsstw@nus.edu.sg.; Department of Research, National Neuroscience Institute, Singapore 308433.; Neurobiology and Ageing Programme, Life Sciences Institute, Centre for Life Sciences, National University of Singapore, Singapore 117456.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore 117456.
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2018 Sep 26; Vol. 38 (39), pp. 8364-8377. Date of Electronic Publication: 2018 Aug 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1529-2401
DOI:10.1523/JNEUROSCI.3262-17.2018