| Title: |
Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position. |
| Authors: |
Cousin D; Pharminox Ltd , Biocity , Pennyfoot St. , Nottingham NG1 1GF , UK., Hummersone MG; Pharminox Ltd , Biocity , Pennyfoot St. , Nottingham NG1 1GF , UK., Bradshaw TD; School of Pharmacy , University of Nottingham , NG7 2RD , UK . Email: tracey.bradshaw@nottingham.ac.uk ; Email: malcolm.stevens@nottingham.ac.uk., Zhang J; School of Pharmacy , University of Nottingham , NG7 2RD , UK . Email: tracey.bradshaw@nottingham.ac.uk ; Email: malcolm.stevens@nottingham.ac.uk., Moody CJ; School of Chemistry , University of Nottingham , NG7 2RD , UK . Email: c.j.moody@nottingham.ac.uk., Foreiter MB; School of Chemistry , University of Nottingham , NG7 2RD , UK . Email: c.j.moody@nottingham.ac.uk., Summers HS; School of Chemistry , University of Nottingham , NG7 2RD , UK . Email: c.j.moody@nottingham.ac.uk., Lewis W; School of Chemistry , University of Nottingham , NG7 2RD , UK . Email: c.j.moody@nottingham.ac.uk., Wheelhouse RT; Institute of Cancer Therapeutics , School of Pharmacy and Medical Sciences , University of Bradford , Bradford , BD7 1DP , UK., Stevens MFG; School of Pharmacy , University of Nottingham , NG7 2RD , UK . Email: tracey.bradshaw@nottingham.ac.uk ; Email: malcolm.stevens@nottingham.ac.uk. |