A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens.

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Title: A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens.
Authors: Hu Z; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Anandappa AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA., Sun J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Kim J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Leet DE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA., Bozym DJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA., Chen C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Williams L; Broad Institute of MIT and Harvard, Cambridge, MA., Shukla SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA., Zhang W; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Tabbaa D; Broad Institute of MIT and Harvard, Cambridge, MA., Steelman S; Broad Institute of MIT and Harvard, Cambridge, MA., Olive O; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Livak KJ; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA., Kishi H; Department of Immunology, University of Toyama, Toyama, Japan., Muraguchi A; Department of Immunology, University of Toyama, Toyama, Japan., Guleria I; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Stevens J; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Lane WJ; Harvard Medical School, Boston, MA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Burkhardt UE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Fritsch EF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA., Neuberg D; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA., Ott PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA; and., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA; and., Hacohen N; Harvard Medical School, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Massachusetts General Hospital, Boston, MA., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA; and.
Source: Blood [Blood] 2018 Nov 01; Vol. 132 (18), pp. 1911-1921. Date of Electronic Publication: 2018 Aug 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood
Database: MEDLINE Ultimate
Description
ISSN:1528-0020
DOI:10.1182/blood-2018-04-843763