Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity.
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| Title: | Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity. |
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| Authors: | Soderquist RS; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Crawford L; Department of Statistics, Duke University, Durham, NC, 27710, USA.; Department of Biostatistics, Brown University School of Public Health, Providence, RI, 02903, USA., Liu E; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Lu M; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Agarwal A; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Anderson GR; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Lin KH; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Winter PS; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Cakir M; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Wood KC; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA. kris.wood@duke.edu. |
| Source: | Nature communications [Nat Commun] 2018 Aug 29; Vol. 9 (1), pp. 3513. Date of Electronic Publication: 2018 Aug 29. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-018-05815-z |