Monosodium urate crystals reduce osteocyte viability and indirectly promote a shift in osteocyte function towards a proinflammatory and proresorptive state.

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Title: Monosodium urate crystals reduce osteocyte viability and indirectly promote a shift in osteocyte function towards a proinflammatory and proresorptive state.
Authors: Chhana A; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand., Pool B; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand., Callon KE; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand., Tay ML; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand., Musson D; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand., Naot D; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand., McCarthy G; Department of Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland., McGlashan S; Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand., Cornish J; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand., Dalbeth N; Department of Medicine, Bone & Joint Research Group, University of Auckland, Auckland, New Zealand. n.dalbeth@auckland.ac.nz.; Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand. n.dalbeth@auckland.ac.nz.
Source: Arthritis research & therapy [Arthritis Res Ther] 2018 Sep 10; Vol. 20 (1), pp. 208. Date of Electronic Publication: 2018 Sep 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1478-6362
DOI:10.1186/s13075-018-1704-y