A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.

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Bibliographic Details
Title: A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.
Authors: Ranzani M; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Alifrangis C; Cancer Genome Project, The Wellcome Trust Sanger Institute, Hinxton, UK.; Division of Cancer, University College London Hospital, London, UK., Thompson NA; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Rust AG; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Tumour Profiling Unit, The Institute of Cancer Research, Chester Beatty Laboratories, London, UK., Allahyar A; Delft Bioinformatics Lab, TU Delft, Delft, The Netherlands., Iyer V; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Price S; Cancer Genome Project, The Wellcome Trust Sanger Institute, Hinxton, UK., Ellis P; Sequencing R&D, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Turner G; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., de Ridder J; Delft Bioinformatics Lab, TU Delft, Delft, The Netherlands.; Centre for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., McDermott U; Cancer Genome Project, The Wellcome Trust Sanger Institute, Hinxton, UK., Adams DJ; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
Source: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2019 Mar; Vol. 32 (2), pp. 332-335. Date of Electronic Publication: 2018 Oct 19.
Publication Type: Letter; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Blackwell Munksgaard Country of Publication: England NLM ID: 101318927 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-148X (Electronic) Linking ISSN: 17551471 NLM ISO Abbreviation: Pigment Cell Melanoma Res
Database: MEDLINE Ultimate
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ISSN:1755-148X
DOI:10.1111/pcmr.12737