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Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.

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Title: Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.
Authors: Van der Jeught K; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium., De Koker S; eTheRNA Immunotherapies NV , Niel 2845 , Belgium., Bialkowski L; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium., Heirman C; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium., Tjok Joe P; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium., Perche F; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France., Maenhout S; eTheRNA Immunotherapies NV , Niel 2845 , Belgium., Bevers S; eTheRNA Immunotherapies NV , Niel 2845 , Belgium., Broos K; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium., Deswarte K; VIB Inflammation Research Center , UGent , Ghent 9052 , Belgium., Malard V; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France., Hammad H; VIB Inflammation Research Center , UGent , Ghent 9052 , Belgium., Baril P; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France., Benvegnu T; Ecole Nationale Supérieure de Chimie de Rennes, CNRS UMR6226 , Rennes 35708 , France., Jaffrès PA; CEMA, CNRS UMR 6521, SFR148 ScInBioS , Université de Brest , Brest 29238 , France., Kooijmans SAA; University Medical Center Utrecht, Universiteit Utrecht , Utrecht 3584 , Netherlands., Schiffelers R; University Medical Center Utrecht, Universiteit Utrecht , Utrecht 3584 , Netherlands., Lienenklaus S; Hannover Medical School , Hannover 30625 , Germany., Midoux P; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France., Pichon C; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France., Breckpot K; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium., Thielemans K; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.
Source: ACS nano [ACS Nano] 2018 Oct 23; Vol. 12 (10), pp. 9815-9829. Date of Electronic Publication: 2018 Oct 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.
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  Data: <searchLink fieldCode="AU" term="%22Van+der+Jeught+K%22">Van der Jeught K</searchLink>; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.<br /><searchLink fieldCode="AU" term="%22De+Koker+S%22">De Koker S</searchLink>; eTheRNA Immunotherapies NV , Niel 2845 , Belgium.<br /><searchLink fieldCode="AU" term="%22Bialkowski+L%22">Bialkowski L</searchLink>; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.<br /><searchLink fieldCode="AU" term="%22Heirman+C%22">Heirman C</searchLink>; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.<br /><searchLink fieldCode="AU" term="%22Tjok+Joe+P%22">Tjok Joe P</searchLink>; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.<br /><searchLink fieldCode="AU" term="%22Perche+F%22">Perche F</searchLink>; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France.<br /><searchLink fieldCode="AU" term="%22Maenhout+S%22">Maenhout S</searchLink>; eTheRNA Immunotherapies NV , Niel 2845 , Belgium.<br /><searchLink fieldCode="AU" term="%22Bevers+S%22">Bevers S</searchLink>; eTheRNA Immunotherapies NV , Niel 2845 , Belgium.<br /><searchLink fieldCode="AU" term="%22Broos+K%22">Broos K</searchLink>; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.<br /><searchLink fieldCode="AU" term="%22Deswarte+K%22">Deswarte K</searchLink>; VIB Inflammation Research Center , UGent , Ghent 9052 , Belgium.<br /><searchLink fieldCode="AU" term="%22Malard+V%22">Malard V</searchLink>; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France.<br /><searchLink fieldCode="AU" term="%22Hammad+H%22">Hammad H</searchLink>; VIB Inflammation Research Center , UGent , Ghent 9052 , Belgium.<br /><searchLink fieldCode="AU" term="%22Baril+P%22">Baril P</searchLink>; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France.<br /><searchLink fieldCode="AU" term="%22Benvegnu+T%22">Benvegnu T</searchLink>; Ecole Nationale Supérieure de Chimie de Rennes, CNRS UMR6226 , Rennes 35708 , France.<br /><searchLink fieldCode="AU" term="%22Jaffrès+PA%22">Jaffrès PA</searchLink>; CEMA, CNRS UMR 6521, SFR148 ScInBioS , Université de Brest , Brest 29238 , France.<br /><searchLink fieldCode="AU" term="%22Kooijmans+SAA%22">Kooijmans SAA</searchLink>; University Medical Center Utrecht, Universiteit Utrecht , Utrecht 3584 , Netherlands.<br /><searchLink fieldCode="AU" term="%22Schiffelers+R%22">Schiffelers R</searchLink>; University Medical Center Utrecht, Universiteit Utrecht , Utrecht 3584 , Netherlands.<br /><searchLink fieldCode="AU" term="%22Lienenklaus+S%22">Lienenklaus S</searchLink>; Hannover Medical School , Hannover 30625 , Germany.<br /><searchLink fieldCode="AU" term="%22Midoux+P%22">Midoux P</searchLink>; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France.<br /><searchLink fieldCode="AU" term="%22Pichon+C%22">Pichon C</searchLink>; Centre de Biophysique Moléculaire, CNRS UPR 4301, University and Inserm , Orléans 45071 , France.<br /><searchLink fieldCode="AU" term="%22Breckpot+K%22">Breckpot K</searchLink>; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.<br /><searchLink fieldCode="AU" term="%22Thielemans+K%22">Thielemans K</searchLink>; Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences , Vrije Universiteit Brussel (VUB) , Brussels 1090 , Belgium.
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  Data: <searchLink fieldCode="JN" term="%22101313589%22">ACS nano</searchLink> [ACS Nano] 2018 Oct 23; Vol. 12 (10), pp. 9815-9829. <i>Date of Electronic Publication: </i>2018 Oct 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101313589 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1936-086X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219360851%22">19360851 </searchLink><i>NLM ISO Abbreviation: </i>ACS Nano <i>Subsets: </i>MEDLINE
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