Human breast tumor-infiltrating CD8+ T cells retain polyfunctionality despite PD-1 expression.
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| Title: | Human breast tumor-infiltrating CD8+ T cells retain polyfunctionality despite PD-1 expression. |
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| Authors: | Egelston CA; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Avalos C; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Tu TY; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Simons DL; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Jimenez G; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Jung JY; Department of Dermatologic Oncology, Norton Cancer Institute, Louisville, KY, 40202, USA., Melstrom L; Department of Surgery, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Margolin K; Department of Medical Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Yim JH; Department of Surgery, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Kruper L; Department of Surgery, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Mortimer J; Department of Medical Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA., Lee PP; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA. plee@coh.org. |
| Source: | Nature communications [Nat Commun] 2018 Oct 16; Vol. 9 (1), pp. 4297. Date of Electronic Publication: 2018 Oct 16. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-018-06653-9 |