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Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.

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Bibliographic Details
Title: Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
Authors: Hu CH; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States. Electronic address: Carol.Hu@bms.com., Wang TC; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States. Electronic address: Tammy.Wang@bms.com., Qiao JX; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Haque L; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Chen AYA; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Taylor DS; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Ying X; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Onorato JM; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Galella M; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Shen H; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Huang CS; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Toussaint N; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Li YX; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Abell L; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Adam LP; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Gordon D; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Wexler RR; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States., Finlay HJ; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2018 Dec 15; Vol. 28 (23-24), pp. 3721-3725. Date of Electronic Publication: 2018 Oct 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1464-3405
DOI:10.1016/j.bmcl.2018.10.022