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Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial).

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Title: Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial).
Authors: Krauter J; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Fiedler W; Department of Oncology, Haematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald University Comprehensive Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Schlenk RF; NCT-Trial Centre, National Centre for Tumour Diseases, Heidelberg, Germany., Paschka P; Department of Internal Medicine III, University of Ulm, Ulm, Germany., Thol F; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Lübbert M; Department of Haematology-Oncology, Faculty of Medicine Freiburg, University of Freiburg Medical Centre, Freiburg, Germany., Wattad M; Evangelisches Krankenhaus Essen-Werden, Essen, Germany., Verbeek M; Department of Internal Medicine III, Technical University of Munich, Munich, Germany., Könecke C; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Neuhaus B; Hannover Clinical Trial Centre, Hannover Medical School, Hannover, Germany., Papkalla A; Hannover Clinical Trial Centre, Hannover Medical School, Hannover, Germany., Kebenko M; Department of Oncology, Haematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald University Comprehensive Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Janning M; Department of Oncology, Haematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald University Comprehensive Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Döhner K; Department of Internal Medicine III, University of Ulm, Ulm, Germany., Gaidzik VI; Department of Internal Medicine III, University of Ulm, Ulm, Germany., Becker H; Department of Haematology-Oncology, Faculty of Medicine Freiburg, University of Freiburg Medical Centre, Freiburg, Germany., Greil C; Department of Haematology-Oncology, Faculty of Medicine Freiburg, University of Freiburg Medical Centre, Freiburg, Germany., Reimer P; Evangelisches Krankenhaus Essen-Werden, Essen, Germany., Götze KS; Department of Internal Medicine III, Technical University of Munich, Munich, Germany., Döhner H; Department of Internal Medicine III, University of Ulm, Ulm, Germany., Ganser A; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Heuser M; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Source: British journal of haematology [Br J Haematol] 2018 Oct; Vol. 183 (2), pp. 235-241.
Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial).
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  Data: <searchLink fieldCode="AU" term="%22Krauter+J%22">Krauter J</searchLink>; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Fiedler+W%22">Fiedler W</searchLink>; Department of Oncology, Haematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald University Comprehensive Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schlenk+RF%22">Schlenk RF</searchLink>; NCT-Trial Centre, National Centre for Tumour Diseases, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Paschka+P%22">Paschka P</searchLink>; Department of Internal Medicine III, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Thol+F%22">Thol F</searchLink>; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Lübbert+M%22">Lübbert M</searchLink>; Department of Haematology-Oncology, Faculty of Medicine Freiburg, University of Freiburg Medical Centre, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wattad+M%22">Wattad M</searchLink>; Evangelisches Krankenhaus Essen-Werden, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Verbeek+M%22">Verbeek M</searchLink>; Department of Internal Medicine III, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Könecke+C%22">Könecke C</searchLink>; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Neuhaus+B%22">Neuhaus B</searchLink>; Hannover Clinical Trial Centre, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Papkalla+A%22">Papkalla A</searchLink>; Hannover Clinical Trial Centre, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Kebenko+M%22">Kebenko M</searchLink>; Department of Oncology, Haematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald University Comprehensive Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Janning+M%22">Janning M</searchLink>; Department of Oncology, Haematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald University Comprehensive Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Döhner+K%22">Döhner K</searchLink>; Department of Internal Medicine III, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Gaidzik+VI%22">Gaidzik VI</searchLink>; Department of Internal Medicine III, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+H%22">Becker H</searchLink>; Department of Haematology-Oncology, Faculty of Medicine Freiburg, University of Freiburg Medical Centre, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Greil+C%22">Greil C</searchLink>; Department of Haematology-Oncology, Faculty of Medicine Freiburg, University of Freiburg Medical Centre, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Reimer+P%22">Reimer P</searchLink>; Evangelisches Krankenhaus Essen-Werden, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Götze+KS%22">Götze KS</searchLink>; Department of Internal Medicine III, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Döhner+H%22">Döhner H</searchLink>; Department of Internal Medicine III, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Ganser+A%22">Ganser A</searchLink>; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Heuser+M%22">Heuser M</searchLink>; Department of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
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  Data: <searchLink fieldCode="JN" term="%220372544%22">British journal of haematology</searchLink> [Br J Haematol] 2018 Oct; Vol. 183 (2), pp. 235-241.
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  Data: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372544 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2141 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071048%22">00071048 </searchLink><i>NLM ISO Abbreviation: </i>Br J Haematol <i>Subsets: </i>MEDLINE
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