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GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors.

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Title: GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors.
Authors: Kazi A; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Xiang S; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Yang H; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Delitto D; Department of Surgery, University of Florida, Gainesville, FL, 32610, USA., Trevino J; Department of Surgery, University of Florida, Gainesville, FL, 32610, USA., Jiang RHY; Department of Global Health and Center for Drug Discovery and Innovation, University of South Florida, Tampa, FL, 33612, USA., Ayaz M; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Lawrence HR; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Kennedy P; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Sebti SM; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. Said.Sebti@moffitt.org.; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. Said.Sebti@moffitt.org.
Source: Nature communications [Nat Commun] 2018 Dec 04; Vol. 9 (1), pp. 5154. Date of Electronic Publication: 2018 Dec 04.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors.
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  Data: <searchLink fieldCode="AU" term="%22Kazi+A%22">Kazi A</searchLink>; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Xiang+S%22">Xiang S</searchLink>; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Delitto+D%22">Delitto D</searchLink>; Department of Surgery, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Trevino+J%22">Trevino J</searchLink>; Department of Surgery, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+RHY%22">Jiang RHY</searchLink>; Department of Global Health and Center for Drug Discovery and Innovation, University of South Florida, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Ayaz+M%22">Ayaz M</searchLink>; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Lawrence+HR%22">Lawrence HR</searchLink>; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Kennedy+P%22">Kennedy P</searchLink>; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Sebti+SM%22">Sebti SM</searchLink>; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. Said.Sebti@moffitt.org.; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. Said.Sebti@moffitt.org.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Dec 04; Vol. 9 (1), pp. 5154. <i>Date of Electronic Publication: </i>2018 Dec 04.
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