GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors.
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| Title: | GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors. |
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| Authors: | Kazi A; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Xiang S; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Yang H; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Delitto D; Department of Surgery, University of Florida, Gainesville, FL, 32610, USA., Trevino J; Department of Surgery, University of Florida, Gainesville, FL, 32610, USA., Jiang RHY; Department of Global Health and Center for Drug Discovery and Innovation, University of South Florida, Tampa, FL, 33612, USA., Ayaz M; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Lawrence HR; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Kennedy P; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Sebti SM; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. Said.Sebti@moffitt.org.; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. Said.Sebti@moffitt.org. |
| Source: | Nature communications [Nat Commun] 2018 Dec 04; Vol. 9 (1), pp. 5154. Date of Electronic Publication: 2018 Dec 04. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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