PLX9486 shows anti-tumor efficacy in patient-derived, tyrosine kinase inhibitor-resistant KIT-mutant xenograft models of gastrointestinal stromal tumors.
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| Title: | PLX9486 shows anti-tumor efficacy in patient-derived, tyrosine kinase inhibitor-resistant KIT-mutant xenograft models of gastrointestinal stromal tumors. |
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| Authors: | Gebreyohannes YK; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Herestraat 49 Post 815, 3000, Leuven, Belgium.; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Burton EA; Plexxikon Inc., Berkeley, CA, USA., Wozniak A; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Herestraat 49 Post 815, 3000, Leuven, Belgium. agnieszka.wozniak@kuleuven.be.; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium. agnieszka.wozniak@kuleuven.be., Matusow B; Plexxikon Inc., Berkeley, CA, USA., Habets G; Plexxikon Inc., Berkeley, CA, USA., Wellens J; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Herestraat 49 Post 815, 3000, Leuven, Belgium.; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Cornillie J; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Herestraat 49 Post 815, 3000, Leuven, Belgium.; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Lin J; Plexxikon Inc., Berkeley, CA, USA., Nespi M; Plexxikon Inc., Berkeley, CA, USA., Wu G; Plexxikon Inc., Berkeley, CA, USA., Zhang C; Plexxikon Inc., Berkeley, CA, USA., Bollag G; Plexxikon Inc., Berkeley, CA, USA., Debiec-Rychter M; Department of Human Genetics, KU Leuven and University Hospitals, Leuven, Belgium., Sciot R; Department of Pathology, KU Leuven and University Hospitals, Leuven, Belgium., Schöffski P; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Herestraat 49 Post 815, 3000, Leuven, Belgium.; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium. |
| Source: | Clinical and experimental medicine [Clin Exp Med] 2019 May; Vol. 19 (2), pp. 201-210. Date of Electronic Publication: 2018 Dec 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100973405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1591-9528 (Electronic) Linking ISSN: 15918890 NLM ISO Abbreviation: Clin Exp Med |
| Database: | MEDLINE Ultimate |
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