Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial.

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Title: Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial.
Authors: Johnston S; 1 The Royal Marsden National Health Service Foundation Trust, London, United Kingdom., Puhalla S; 2 Univeristy of Pittsburgh Medical Center Cancer Center, Pittsburgh, PA., Wheatley D; 3 Royal Cornwall Hospitals National Health Service Foundation Trust, Treliske, United Kingdom., Ring A; 1 The Royal Marsden National Health Service Foundation Trust, London, United Kingdom., Barry P; 1 The Royal Marsden National Health Service Foundation Trust, London, United Kingdom., Holcombe C; 4 Royal Liverpool and Broadgreen University Hospitals National Health Service Trust, Liverpool, United Kingdom., Boileau JF; 5 Montreal Jewish General Hospital Segal Cancer Centre, Montreal, Quebec, Canada., Provencher L; 6 Centre Hospitalier Université de Quebec-Universite Laval, Quebec City, Quebec, Canada., Robidoux A; 7 Centre Hospitalier Université de Montréal, Montreal, Quebec, Canada., Rimawi M; 8 Baylor College of Medicine, Houston, TX., McIntosh SA; 9 Queen's University Belfast, Belfast, United Kingdom., Shalaby I; 10 Joe Arrington Cancer Research and Treatment Center, Lubbock, TX., Stein RC; 11 National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, United Kingdom.; 12 University College London Hospitals National Health Service Foundation Trust, London, United Kingdom., Thirlwell M; 13 McGill University Health Centre, Montreal, Quebec, Canada., Dolling D; 14 The Institute of Cancer Research, London, United Kingdom., Morden J; 14 The Institute of Cancer Research, London, United Kingdom., Snowdon C; 14 The Institute of Cancer Research, London, United Kingdom., Perry S; 14 The Institute of Cancer Research, London, United Kingdom., Cornman C; 15 National Surgical Adjuvant Breast and Bowel Project Foundation, Pittsburgh, PA., Batten LM; 14 The Institute of Cancer Research, London, United Kingdom., Jeffs LK; 14 The Institute of Cancer Research, London, United Kingdom., Dodson A; 1 The Royal Marsden National Health Service Foundation Trust, London, United Kingdom.; 14 The Institute of Cancer Research, London, United Kingdom., Martins V; 1 The Royal Marsden National Health Service Foundation Trust, London, United Kingdom., Modi A; 1 The Royal Marsden National Health Service Foundation Trust, London, United Kingdom., Osborne CK; 8 Baylor College of Medicine, Houston, TX., Pogue-Geile KL; 15 National Surgical Adjuvant Breast and Bowel Project Foundation, Pittsburgh, PA., Cheang MCU; 14 The Institute of Cancer Research, London, United Kingdom., Wolmark N; 15 National Surgical Adjuvant Breast and Bowel Project Foundation, Pittsburgh, PA., Julian TB; 16 Allegheny Health Network Cancer Institute, Pittsburgh, PA., Fisher K; 17 International Drug Development Institute, Brussels, Belgium., MacKenzie M; 18 Independent Cancer Patients Voice, London, United Kingdom., Wilcox M; 18 Independent Cancer Patients Voice, London, United Kingdom., Huang Bartlett C; 19 Pfizer, New York, NY., Koehler M; 20 Bicycle Therapeutics, Boston, MA., Dowsett M; 1 The Royal Marsden National Health Service Foundation Trust, London, United Kingdom.; 14 The Institute of Cancer Research, London, United Kingdom., Bliss JM; 14 The Institute of Cancer Research, London, United Kingdom., Jacobs SA; 15 National Surgical Adjuvant Breast and Bowel Project Foundation, Pittsburgh, PA.
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2019 Jan 20; Vol. 37 (3), pp. 178-189. Date of Electronic Publication: 2018 Dec 06.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1527-7755
DOI:10.1200/JCO.18.01624