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HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.

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Title: HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.
Authors: Zheng J; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. jzheng@scripps.edu., Wang C; Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Chang MR; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA., Devarkar SC; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA., Schweibenz B; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA., Crynen GC; The Center for Computational Biology, The Scripps Research Institute, Jupiter, FL, 33458, USA., Garcia-Ordonez RD; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA., Pascal BD; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.; Omics Informatics LLC, Honolulu, HI 96813, USA., Novick SJ; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA., Patel SS; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA., Marcotrigiano J; Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. joseph.marcotrigiano@nih.gov., Griffin PR; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. pgriffin@scripps.edu.
Source: Nature communications [Nat Commun] 2018 Dec 18; Vol. 9 (1), pp. 5366. Date of Electronic Publication: 2018 Dec 18.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.
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  Data: <searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. jzheng@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Chang+MR%22">Chang MR</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Devarkar+SC%22">Devarkar SC</searchLink>; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA.<br /><searchLink fieldCode="AU" term="%22Schweibenz+B%22">Schweibenz B</searchLink>; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA.<br /><searchLink fieldCode="AU" term="%22Crynen+GC%22">Crynen GC</searchLink>; The Center for Computational Biology, The Scripps Research Institute, Jupiter, FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Garcia-Ordonez+RD%22">Garcia-Ordonez RD</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Pascal+BD%22">Pascal BD</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.; Omics Informatics LLC, Honolulu, HI 96813, USA.<br /><searchLink fieldCode="AU" term="%22Novick+SJ%22">Novick SJ</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Patel+SS%22">Patel SS</searchLink>; Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, 08854, USA.<br /><searchLink fieldCode="AU" term="%22Marcotrigiano+J%22">Marcotrigiano J</searchLink>; Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. joseph.marcotrigiano@nih.gov.<br /><searchLink fieldCode="AU" term="%22Griffin+PR%22">Griffin PR</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA. pgriffin@scripps.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2018 Dec 18; Vol. 9 (1), pp. 5366. <i>Date of Electronic Publication: </i>2018 Dec 18.
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