Heterozygous Pkhd1C642* mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney.

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Title: Heterozygous Pkhd1C642* mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney.
Authors: Shan D; Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama., Rezonzew G; Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama., Mullen S; Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama., Roye R; Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama., Zhou J; Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama., Chumley P; Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama., Revell DZ; Department of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham , Birmingham, Alabama., Challa A; Department of Genetics, The University of Alabama at Birmingham , Birmingham, Alabama., Kim H; Department of Radiology, The University of Alabama at Birmingham , Birmingham, Alabama., Lockhart ME; Department of Radiology, The University of Alabama at Birmingham , Birmingham, Alabama., Schoeb TR; Department of Genetics, The University of Alabama at Birmingham , Birmingham, Alabama., Croyle MJ; Department of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham , Birmingham, Alabama., Kesterson RA; Department of Genetics, The University of Alabama at Birmingham , Birmingham, Alabama., Yoder BK; Department of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham , Birmingham, Alabama., Guay-Woodford LM; Center for Translational Science, Children's National Health System , Washington, District of Columbia., Mrug M; Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama.; Department of Veterans Affairs Medical Center , Birmingham, Alabama.
Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2019 Mar 01; Vol. 316 (3), pp. F463-F472. Date of Electronic Publication: 2019 Jan 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1522-1466
DOI:10.1152/ajprenal.00181.2018