Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood-brain barrier.
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| Title: | Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood-brain barrier. |
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| Authors: | Hoshi Y; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan., Uchida Y; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan., Tachikawa M; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan., Ohtsuki S; Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Couraud PO; Institut Cochin, Inserm U1016, CNRS UMR8104, Paris Descartes University, Paris, France., Suzuki T; Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, Sendai, Japan., Terasaki T; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan. |
| Source: | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2020 Feb; Vol. 40 (2), pp. 420-436. Date of Electronic Publication: 2019 Jan 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1559-7016 |
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| DOI: | 10.1177/0271678X18822801 |
