Invertible promoters mediate bacterial phase variation, antibiotic resistance, and host adaptation in the gut.
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| Title: | Invertible promoters mediate bacterial phase variation, antibiotic resistance, and host adaptation in the gut. |
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| Authors: | Jiang X; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Hall AB; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Arthur TD; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Plichta DR; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Covington CT; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Poyet M; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Crothers J; Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, VT 05401, USA., Moses PL; Division of Gastroenterology and Hepatology, University of Vermont, Burlington, VT 05401, USA., Tolonen AC; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Vlamakis H; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Alm EJ; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. xavier@molbio.mgh.harvard.edu ejalm@mit.edu.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Xavier RJ; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. xavier@molbio.mgh.harvard.edu ejalm@mit.edu.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. |
| Source: | Science (New York, N.Y.) [Science] 2019 Jan 11; Vol. 363 (6423), pp. 181-187. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science |
| Database: | MEDLINE Ultimate |
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