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An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z.

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Title: An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z.
Authors: Wang Y; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Cobanoglu MC; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Li J; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Hidvegi T; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Hale P; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Ewing M; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Chu AS; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Gong Z; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Muzumdar R; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Pak SC; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Silverman GA; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Bahar I; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Perlmutter DH; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Source: PloS one [PLoS One] 2019 Jan 23; Vol. 14 (1), pp. e0209748. Date of Electronic Publication: 2019 Jan 23 (Print Publication: 2019).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Cobanoglu+MC%22">Cobanoglu MC</searchLink>; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Hidvegi+T%22">Hidvegi T</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Hale+P%22">Hale P</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Ewing+M%22">Ewing M</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Chu+AS%22">Chu AS</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Gong+Z%22">Gong Z</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Muzumdar+R%22">Muzumdar R</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Pak+SC%22">Pak SC</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Silverman+GA%22">Silverman GA</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Bahar+I%22">Bahar I</searchLink>; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Perlmutter+DH%22">Perlmutter DH</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
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