Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy.

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Title: Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy.
Authors: Hughes MC; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada., Ramos SV; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada., Turnbull PC; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada., Edgett BA; Department of Human Health and Nutritional Sciences and Cardiovascular Research Group, University of Guelph, Guelph, ON, Canada.; Department of Pharmacology, Dalhousie Medicine New Brunswick, Saint John, New Brunswick, Canada.; IMPART Team Canada Investigator Network, Saint John, New Brunswick, Canada., Huber JS; Department of Human Health and Nutritional Sciences and Cardiovascular Research Group, University of Guelph, Guelph, ON, Canada., Polidovitch N; Department of Biology and the Muscle Health Research Centre, York University, Toronto, ON, Canada., Schlattner U; Laboratory of Fundamental and Applied Bioenergetics (LBFA) and SFR Environmental and Systems Biology (BEeSy), University Grenoble Alpes, Grenoble, France., Backx PH; Department of Biology and the Muscle Health Research Centre, York University, Toronto, ON, Canada., Simpson JA; Department of Human Health and Nutritional Sciences and Cardiovascular Research Group, University of Guelph, Guelph, ON, Canada.; IMPART Team Canada Investigator Network, Saint John, New Brunswick, Canada., Perry CGR; School of Kinesiology and Health Science and the Muscle Health Research Centre, York University, Toronto, ON, Canada.
Source: The Journal of physiology [J Physiol] 2020 Apr; Vol. 598 (7), pp. 1377-1392. Date of Electronic Publication: 2019 Feb 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-7793
DOI:10.1113/JP277306