Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.
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| Title: | Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph. |
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| Authors: | Magno L; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK. l.magno@ucl.ac.uk., Lessard CB; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Martins M; Research Department of Structural and Molecular Biology, University College London, London, UK.; Present address: Instituto de Medicina Molecular - João Lobo Antunes, Faculdade de Medicina de Lisboa, Lisbon, Portugal., Lang V; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK., Cruz P; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Asi Y; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, UK., Katan M; Research Department of Structural and Molecular Biology, University College London, London, UK., Bilsland J; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK., Lashley T; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, UK., Chakrabarty P; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Golde TE; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA., Whiting PJ; UCL Alzheimer's Research UK, Drug Discovery Institute, London, UK. p.whiting@ucl.ac.uk.; Dementia Research Institute, UCL, London, UK. p.whiting@ucl.ac.uk. |
| Source: | Alzheimer's research & therapy [Alzheimers Res Ther] 2019 Feb 02; Vol. 11 (1), pp. 16. Date of Electronic Publication: 2019 Feb 02. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1758-9193 |
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| DOI: | 10.1186/s13195-019-0469-0 |
