Evaluation of 11C-LSN3172176 as a Novel PET Tracer for Imaging M1 Muscarinic Acetylcholine Receptors in Nonhuman Primates.

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Title: Evaluation of 11C-LSN3172176 as a Novel PET Tracer for Imaging M1 Muscarinic Acetylcholine Receptors in Nonhuman Primates.
Authors: Nabulsi NB; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and nabeel.nabulsi@yale.edu., Holden D; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Zheng MQ; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Bois F; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Lin SF; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Najafzadeh S; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Gao H; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Ropchan J; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Lara-Jaime T; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Labaree D; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Shirali A; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Slieker L; Eli Lilly and Co., Indianapolis, Indiana., Jesudason C; Eli Lilly and Co., Indianapolis, Indiana., Barth V; Eli Lilly and Co., Indianapolis, Indiana., Navarro A; Eli Lilly and Co., Indianapolis, Indiana., Kant N; Eli Lilly and Co., Indianapolis, Indiana., Carson RE; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and., Huang Y; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT; and.
Source: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2019 Aug; Vol. 60 (8), pp. 1147-1153. Date of Electronic Publication: 2019 Feb 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1535-5667
DOI:10.2967/jnumed.118.222034